Good News For Women With Breast Cancer, Many Do Not Need Chemotherapy

Many women around the world live a daily ordeal in fighting cancer. But among the cancers specifically targeting women, we can easily ment...

Many women around the world live a daily ordeal in fighting cancer. But among the cancers specifically targeting women, we can easily mention the one of the breast, which remains the most frequent case in France and concerns alone 31% of French people with cancer.

A study capable of changing our vision of the treatment of this cancer
A recent international study, reported by The New York Times, may be able to change the treatment of breast cancer since it proves that many women today with breast cancer and chemotherapy the rules in force do not really need it.

Dr. Ingrid Mayer of Vanderbilt University, who is also the author of the study, says, "We can totally save thousands and thousands of women from toxic treatments that really do not benefit them and that can change a lot of things. "

The study revealed that genetic tests on tumor samples make it possible to determine whether a patient can be safely given chemotherapy and should therefore only take a drug that blocks the activity of the patient. the hormone estrogen or that prevents its production in the body. Tamoxifen, a hormone inhibitor and other similar drugs known as endocrine therapy, are now an essential part of the treatment for many women as they drastically reduce the risk of recurrence of the disease and the risk of death. .

Very encouraging progress
Dr. Larry Norton of the Memorial Sloan Kettering Cancer Center in New York has, although not himself the author of the study, participated in this one. In fact, he says, "I can finally look people in the eye and say, 'We have analyzed your tumor, you have a very good prognosis and you do not really need chemotherapy! It's so good to be able to say that to someone! "

Such results clearly affect about 60,000 women per year in the United States according to Dr. Joseph Sparano of the Montefiore Medical Center in New York and head of the study: "The results indicate that we can now save about 70% chemotherapy. patients who are potential candidates based on the clinical characteristics they present. "

The study called "TAILORx" was published in the New England Journal of Medicine and began in 2006. Its funding was jointly supported by the US and Canadian governments as well as by philanthropic groups. Knowing that Genomic Health, the company responsible for genetic testing contributed to the financing from 2016.

A very good alternative but not without risks
Chemotherapy can certainly save lives, but carries too many risks that make avoiding it very often preferable especially if it is not necessary. Because in addition to the hair loss and nausea it can cause in patients, chemotherapy can cause heart and nerve damage and make patients vulnerable to different infections and increase the risk of leukemia later. "TAILORx" therefore aims to make the treatment as safe as possible by avoiding side effects as soon as it is feasible.

Endocrine therapy, on the other hand, is not free from unpleasant side effects that may include hot flashes and other menopausal-like symptoms, as well as joint and muscle pain and weight gain. It is important to note that Tamoxifen may increase the risk of developing cancer of the uterus.

The genetic test, called the Oncotype DX breast cancer test, costs around $ 3,000 and is at the center of the study. Although other similar tests exist, this one remains the most used in the United States. It is performed on tumor samples after surgery to determine whether the chemotherapy is able to help the patient. The test is also performed for people in the early stages of the disease but not for more advanced stage tumors as they have already spread and affect the lymph nodes or more.
Good News For Women With Breast Cancer, Many Do Not Need Chemotherapy

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Savvy Life Mag Plus: Good News For Women With Breast Cancer, Many Do Not Need Chemotherapy
Good News For Women With Breast Cancer, Many Do Not Need Chemotherapy
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