This Little Cancer Survivor Is The Bridesmaid At The Wedding Of Her Bone Marrow Donor

In the alley leading to the bride at a wedding, walked a little girl of 3 years holding in her hands a bouquet of flowers; she radiate...

This Little Cancer Survivor Is The Bridesmaid At The Wedding Of Her Bone Marrow Donor

In the alley leading to the bride at a wedding, walked a little girl of 3 years holding in her hands a bouquet of flowers; she radiated joy and happiness. This girl had juvenile myelomonocytic leukemia (LMMJ) and was saved by the 26-year-old bride who invited her to her wedding to be her bridesmaid.

Skye Savren-McCormick, a 3-year-old girl, hit a number of guests at the wedding of 26-year-old Hayden Hatfield Ryals. The little girl was diagnosed with juvenile myelomonocytic leukemia just before her first birthday. However, she was saved by Ryals who donated her bone marrow through a transplant in the same year. After that, Skye managed to defeat leukemia.

A few months later, Skye's parents received an invitation to their grandson from Ryals, inviting the girl to become her bridesmaid at her wedding.

A friendship was born between Skye and Ryals and the image of these two people linked by this love was moving and made most guests cry.

Skye's family is grateful to Ryals for saving their daughter's life, and vowing to stay together forever.

What is juvenile myelomonocytic leukemia (LMMJ)?

The LMMJ is a rare type of blood cancer that develops rapidly if not treated in time. This disease mainly affects young children or children under six and affects boys more than girls. Every year, ten cases are counted in France.

This disease has the same characteristics of two other blood cancers, which is why it is classified by the World Health Organization (WHO) as a mixed myelodysplastic disease.
This Little Cancer Survivor Is The Bridesmaid At The Wedding Of Her Bone Marrow Donor

How is the LMMJ?

The LMMJ is triggered following a modification of the DNA (genetic character) of a stem cell of the bone marrow. These stem cells contribute to the formation of white blood cells, red blood cells and platelets.

This change mainly affects one type of white blood cell, monocyte, and transforms it into a leukemic cell, in other words, cancerous.

The role of monocytes in combination with other white blood cells called neutrophils is to neutralize microbes and germs in the blood. Moreover, by penetrating the tissues, monocytes help to fight the infection and to help each other with other cells to strengthen the immune system.

The proliferation of leukemic cells leads to a considerable decrease in healthy blood cells such as red blood cells, white blood cells and platelets.

The symptoms of the LMMJ
The symptoms are not long in being felt. Thus we see in children:
  • The appearance of anemia is characterized by fatigue and pallor due to a decrease in red blood cells.
  • The occurrence of frequent haemorrhages.
  • Exposure to infections
  • Fever.
  • The increase in the size of the ganglia.
  • The cutaneous affection.

How is the diagnosis made?
Several examinations are then performed to determine the existence of the pathology:
  • blood test
  • blood smear
  • bone marrow puncture

What is the treatment of the LMMJ?
In most cases, this childhood leukemia is treated with either chemotherapy combined with other medications, a bone marrow transplant, or targeted therapy. In all cases, these treatments require hospitalization in a sterile room since the child's immune system becomes too weak to fight infections.

Through these treatments, patients can sometimes be cured. Note also that bone marrow transplant is an operation that is not 100% guaranteed because of the risk of rejection that remains predominant.

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