Scientists Come To Discover The True Cause Of Colon Cancer

Colon cancer is a disease that develops from cells in the lining of the colon, that is, in the middle part of the large intestine, located...

Colon cancer is a disease that develops from cells in the lining of the colon, that is, in the middle part of the large intestine, located between the caecum and the rectum. The colon represents most of the large intestine. Because cancers of the colon and rectum are fairly close, they are often grouped under the term colorectal cancer.

As with all cancers, several risk factors may predispose to colon cancer such as lifestyle factors, including smoking, unhealthy diet, genetic predisposition, and environmental factors, which include pollution and illness. handling of toxic substances.

In France, there are no less than 37,000 cases per year and 18,000 people die of colorectal cancer. Moreover, cancer of the colon, in addition to that of the lungs, liver, stomach and breast are among the cancers that cause the greatest number of deaths each year.

This form of cancer that develops from cells of the lining of the colon, in the middle part of the large intestine, located between the caecum and the rectum is more commonly known as colorectal cancer since the colon and rectum are made of the same tissues and that there is no limit established between them.

Study finds link between cellular stress and colon cancer
A study conducted by the Technical University of Munich focusing on the role of bacteria in the development of inflammatory bowel diseases, has shown that cellular stress and the association of microbiota modification (good balance and bad bacteria that populate our intestinal digestive system in the colon and stimulate tumor growth without inflammation.

Indeed, the study in question focused on the analysis of germ-free sterile mice to which intestinal mucosa was introduced, a transcription factor called ATF6, and no significant changes in possible developing tumors were detected. . On the other hand, as soon as the intestinal microbiota was transplanted into the control mice, tumors were developed in their colon, whereas at the beginning the science considered that cell stress and bacterial flora were responsible only for diseases inflammatory bowel.

Professor Dirk Haller, researcher and co-author of the study, says and confirms that it is not the cellular stress that leads to the growth of the tumor, but the association of stress and modification of the gut microbiota that promote the development of colon cancer.

Testing of ATF6 in patients with colon cancer
In association with the Isar Clinic of the Technical University of Munich, the medical data of 541 colon cancer patients were analyzed taking into account the ATF6 transmission factor. Analysis that clearly showed that this factor and the rate of colon cancer both worked in close collaboration.

In other words, the rate of colon cancer was significantly increased and recurrences after surgery were more numerous; about 10% of patients were at risk of colon cancer again.

For Professor Haller, a microbial therapy would be unequivocal, plausible with regard to the composition of the bacterial flora.

Prevention of colorectal cancer
In order to prevent any risk, it is highly recommended that men and women aged 50 and over have a stool test performed using an immunochemical FOBT test or with the help of Guaiac test at least every 2 years. In case of family history, it is also advisable to have a sigmoidoscopy or a colonoscopy at the age of 40 years.

Any practice of prevention of colorectal cancer also involves the use and maintenance of a healthy lifestyle including stopping smoking and limiting the consumption of alcohol, red meats or cold cuts, the practice of Regular physical exercises and a healthy diet.
Scientists Come To Discover The True Cause Of Colon Cancer

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Savvy Life Mag Plus: Scientists Come To Discover The True Cause Of Colon Cancer
Scientists Come To Discover The True Cause Of Colon Cancer
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