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Getting Up Early Reduces The Risk Of Developing Breast Cancer, According To A Study



From our consumption of food and alcohol to the use of the contraceptive pill, women are regularly asked to remain vigilant when it comes ...

From our consumption of food and alcohol to the use of the contraceptive pill, women are regularly asked to remain vigilant when it comes to reducing the risk of breast cancer. However, we did not think that our biological clocks could have a role to play. British researchers now say that getting up early would reduce the risk of breast cancer.

The study
A team from the University of Bristol led by Dr. Rebecca Richmond, associate researcher at the Cancer Research UK Epidemiology Unit in Bristol, presented a study at the Cancer Conference at NCRI (National Cancer Institute) in Glasgow that suggests that early birds are 40-48% less likely to develop breast cancer than night eaters.

Using a new method of data analysis - called Mendelian randomization - researchers have studied 341 DNA segments that control the clocks of our body.

The study also found an additional risk of breast cancer in women who slept more than the recommended duration of seven to eight hours per night, which equates to an additional risk of 20% per hour of sleep.

However, the team pointed out that the development of breast cancer was linked to many factors and that these figures did not represent an absolute risk. In addition, the results can not be applied to all populations because the majority of women included were of European origin.

What does that mean ?
"Sleep is probably a significant risk factor for breast cancer, but it is not as important as other well-established risk factors, such as body mass index (BMI) or alcohol," said Dr. Richmond.

"We know that sleep is generally important for health. These findings can potentially influence the sleep patterns of the general population to improve health and reduce the risk of breast cancer in women. "

Our circadian rhythms, or biological clocks, control the body's functions such as sleep patterns, blood pressure and metabolism. When disturbed, they can increase the risk of cancer and other diseases.

Dr. Richmond's team conducted their genetic analysis in hopes of better understanding the possible causes and consequences of this link. However, experts caution that more research is needed and that existing results can not be applied more widely.

"The statistical method used in this study does not always make it possible to establish a causal inference," said Dipender Gill, clinical researcher at Imperial College London. "For example, genetic determinants of sleep can also affect other neural mechanisms that affect breast cancer risk regardless of sleep patterns. In such a scenario, the latter may be associated with the risk of breast cancer, but not directly. "

Sleep, not as important as other factors
Night owls should not be worried about the results, she adds. "I would not argue that women should get up earlier to reduce the risk of breast cancer. "

There are theories about the causes of the effect of sleep on cancer, she explained, such as the idea that artificial night light causes hormonal disturbances.

Dr. Sowmiya Moorthie, Senior Policy Analyst in Epidemiology at the PHG Foundation in Cambridge who did not participate in the research, added that the major strength of the study lies in the use of "multiple approaches to examine the links between sleep characteristics and breast cancer, which allows researchers to demonstrate consistency in their results. "

"Regarding the implications of the research, they corroborate the existing evidence that sleep patterns affect cancer risk, but it is still unclear how individual preferences for early or late awakening interact with cancer behaviors. real sleep, "wrote Moorthie in an email.
Getting Up Early Reduces The Risk Of Developing Breast Cancer, According To A Study